Sometimes you end up running many databases on the same machine. These might have very different needs. For example, one may handle user sessions (updated frequently but with tiny amounts of data), and another may contain large sets of data that are hardly ever updated. You might be able to improve performance by running two differently tuned database servers on one machine. The frequently updated database can gain a lot from fast disk access, whereas the database with mostly static data could benefit from lots of caching.
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